Clinical and scientific focus

• Individualized biological reconstruction procedures, especially diseases of the aorta, pelvic and leg arteries
• Open surgical and endovascular therapy methods for aortic diseases
• Evaluation and implementation of digital technologies such as 3D image processing and 3D printing, navigation and virtual reality
• Modulation of endothelial cell function through proinflammatory and proapaptotic signaling pathways in the context of atherosclerosis
• Academic and clinical background
• 1990-1997    Study of human medicine at Johannes Gutenberg University in Mainz with stays abroad in Boston, MA, USA (Harvard Medical School), Basel, Switzerland (University Hospital) and Houston, TX, USA (Baylor College of Medicine)
• 1997-2004    Scientific assistant (rotation) in further training to become a specialist in surgery at the Mainz University Hospital with Prof. Dr. H. Oelert (Clinic for Cardiac, Thoracic and Vascular Surgery), Prof. Dr. PM Rommens (trauma surgery) and Prof. Dr. Th. Junginger (general and abdominal surgery) 
• 07/1998    Doctorate to Dr. med. by the medical faculty of the University of Mainz
• 06/1999    approbation as Doctor
• 03/2004    ECFMG Certificate (American Medical Examination) with unlimited validity
• 09/2004    Recognition as a specialist in surgery
• 10 / 2004-09 / 2006    Further training in the field of vascular surgery at the Clinic for Cardiac, Thoracic and Vascular Surgery of the University Clinic Mainz (Director Prof. Dr. C.-F. Vahl)
• 10/2006    Appointment as senior physician at the Clinic for Cardiac, Thoracic and Vascular Surgery at the University Clinic Mainz (Director Prof. Dr. C.-F. Vahl)
• 10/2006    Recognition as a specialist in vascular surgery
• 04/2007    Appointment as managing senior physician in the field of vascular surgery at the Clinic for Cardiac, Thoracic and Vascular Surgery at the Mainz University Clinic (Director Prof. Dr. C.-F. Vahl)
• 02 / 2008-01 / 2009    Research stay at Columbia University, New York, NY, USA (visiting professor: Ira Tabas, MD Ph.D., Dept. of Molecular Medicine, DFG funded)
• 12/2008    Habilitation and award of the Venia legendi for the subject vascular surgery
• 04/2010    Appointment as head of the vascular surgery section of the Clinic for Cardiac, Thoracic and Vascular Surgery at the Mainz University Hospital (Director Prof. Dr. C.-F. Vahl)
• 01/2012    Head of the DFG research project (Do1289 / 6-1), duration 3 years
• 08/2013    Lead applicant for 3x certification as a university vascular center (DGG, DGA, DRG)
• 02/2015    Appointment as adjunct professor
• 03/2015    Appointment as Deputy Clinic Director of the Clinic for Cardiac, Thoracic and Vascular Surgery at the Mainz University Clinic
• 07/2017    Election as spokesman for the internal university research focus BiomaTiCS (term of office 2 years)
• 04/2020    Acceptance of the W3 professorship for Vascular Surgery at the University of Cologne in connection with the Directorate of the Clinic and Polyclinic for Vascular Surgery - Vascular and Endovascular Surgery at the University Hospital Cologne

Selected additional qualifications

• 01/2011    Expertise in radiation protection (thorax, vascular system and interventions)
• 05/2012    Certificate Endovascular Surgeon (German Society for Vascular Surgery)
• 07/2014    Investigator course MPG studies
• 09/2017–04/2018    Intensive study of health economics with certificate "health economist" at the European Business School, Health Care Management Institute, Oestrich-Winkel (overall grade 1.4 / ECTS grade A ("excellent"))
• Prizes, awards and grants
• 1995    Doctoral scholarship from the University of Mainz
• 2004-2006    Research grant for the promotion of young talent from the University of Mainz (MAIFOR)
• 2006    Research award from the Robert Müller Foundation of the University of Mainz
• 200-2009    Research grant from the Rhineland-Palatinate Foundation for Innovation
• 2007    Rudolf-Stich Prize of the German Society for Thoracic, Cardiac and Vascular Surgery
• 2007-2008    Research grant from the Karl & Lore Klein Foundation of the German Society for Arteriosclerosis Research
• 2008    Travel grant from the German Society for Surgery
• 2008    Research grant from the German Research Foundation (DO 1289 / 2-1) at Columbia University, New York, NY, USA
• 2010    Karl Kremer Prize of the German Society for Vascular Surgery
• 2011    Poster award of the German Society for Surgery
• 2013    Poster award of the European Society for Vascular Surgery

Memberships

• German Society for Surgery
• German Society for Vascular Surgery
• German Society for Thoracic, Cardiac and Vascular Surgery
• European Society for Vascular Surgery (ESVS)
• Society for Vascular Surgery (SVS)
• Association for 3D printing in medicine
• Wound Commission of the German Society for Vascular Surgery
• Deputy Chair of the “Artificial Intelligence and Digital Systems” commission of the German Society for Vascular Surgery

Activity as a reviewer

• European Journal of Trauma and Emergency Surgery (Board member / Section Editor)
• Vascular Surgery (Board member)
• Thoracic and Cardiovascular Surgeon
• Annals of Vascular Surgery
• Journal of Endovascular Therapy
• European Surgical Research
• Clinical Chemistry and Laboratory Medicine
• Cytotherapy

Selected publications

• Dorweiler B , Neufang A, Kreitner KF, Schmiedt W, Oelert H. Magnetic resonance angiography unmasks reliable target vessels for pedal bypass grafting in patients with diabetes mellitus Journal of Vascular Surgery, 2002 ; 35: 766-72
• Dorweiler B , Torzewski M, Dahm M, Ochsenhirt V, Lehr HA, Lackner KJ, Vahl CF. A novel in vitro model for the study of plaque development in atherosclerosis Thrombosis Haemostasis 2006 ; 95: 182-189
• Dorweiler B , Torzewski M, Dahm M, Kirkpatrick CJ, Lackner KJ, Vahl CF. Subendothelial infiltration of granulocytes and liberation of matrix degrading enzymes in an in vitro model of human neo-intima. Thrombosis Haemostasis 2008 ; 99: 373-381
• Woo CW, Cui D, Arellano J, Dorweiler B , Harding H, Fitzgerald KA, Ron D, Tabas I. Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signaling. Nature Cell Biol. 2009 ; 11: 1473-80.
• Dorweiler B , Weigang E, Duenschede F, Pitton MB, Dueber C, Vahl CF. Strategies for Endovascular Aortic Repair in Aortobronchial and Aortoesophageal Fistulas. Thorac Cardiovasc Surg. Thorac Cardiovasc Surg. 2013 ; 61: 575-80.
• Dorweiler B , Neufang A, Chaban R, Reinstadler J, Duenschede F, Vahl CF. Use and durability of femoral vein for autologous reconstruction with infection of the aortoiliofemoral axis. J Vasc Surg. 2014 ; 59: 675-83
• Dorweiler B , Gemechu A, Doemland M, Neufang A, Espinola-Klein C, Vahl CF. Durability of open popliteal artery aneurysm repair. J Vasc Surg 2014, 2014 ; 60: 951-7
• Dorweiler B , Grechowa I, Wallrath A, Vahl CF, Horke S. Activation of the proapoptotic unfolded protein response in plaques of the human carotid artery. Eur J Vasc Endovasc Surg 2014 , 48: 248-57
• Youssef M, Neufang A, Jungmann F, CF Vahl, Dorweiler B . Patency of renal and visceral vessels after open thoracoabdominal aortic replacement. J Vasc Surg. 2015 Sep; 62 (3): 594-9
• Heller M, Bauer HK, Goetze E, Gielisch M, Roth KE, Drees P, Maier GS, Dorweiler B , Ghazy A, Neufurth M, Müller WE, Schröder HC, Wang X, Vahl CF, Al-Nawas B. Applications of patient -specific 3D printing in medicine. Int J Comput Dent. 2016 ; 19 (4): 323-339
• Dorweiler B , Boedecker C, Dünschede F, Vahl CF, Youssef M. 3D-Analysis of component stability of the Nellix® endovascular aneurysm sealing (EVAS) technology after treatment of infrarenal abdominal aortic aneurysms. J Endovasc Ther. 2017 Apr; 24 (2): 201-209
• Youssef M, Salem O, Dünschede F, CF Vahl, Dorweiler B . Adjunct Perfusion Branch for Reduction of Spinal Cord Ischemia in the Endovascular Repair of Thoracoabdominal Aortic Aneurysms. Thorac Cardiovasc Surg. 2018 Apr; 66 (3): 233-239
• Grechowa I Horke S, spermaceti A, Vahl CF, Dorweiler B . Human neutrophil elastase induces endothelial cell apoptosis by activating the PERK-CHOP branch of the unfolded protein response. FASEB J 2017 Sep; 31 (9): 3868-3881
• Dorweiler B , Trinh TT, Dünschede F, Vahl CF, Debus ES, Storck M, Diener H. The marine Omega3 wound matrix for treatment of complicated wounds: A multicenter experience report. Vascular surgery. 2018 ; 23 (Suppl 2): ??46-55
• Ghazy A, R Chaban, Vahl CF, Dorweiler B . Development and evaluation of 3D-printed models of the human tracheobronchial system for training in flexible bronchoscopy. Interact Cardiovasc Thorac Surg. 2019 Jan 1; 28 (1): 137-143
• Dorweiler B , Vahl CF, Ghazy A. Future prospects for digital visualization technologies in vascular surgery: Augmented Reality, Virtual Reality and 3D printing. Vascular surgery, 2019 ; 24: 531-538
• Dorweiler B , El Beyrouti H, Vahl CF, Baqué PE, Ghazy A. The Future of Vascular Medicine - Role of 3D Printing. Zentralbl Chir. 2020 Jan 15. doi: 10.1055 / a-1084-5499.
• Krumb H, Hofmann S, Kügler D, Ghazy A, Dorweiler B , Bredemann J, Schmitt R, Sakas G, Mukhopadhyay A. Leveraging spatial uncertainty for online error compensation in EMT. Int J Comput Assist Radiol Surg. 2020 May 22. doi: 10.1007 / s11548-020-02189